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The DKFZ researcher received the €100,000 award for his work on cancer metabolism. What determines whether breast cancer cells can form metastases?


In most cancers, it is not the growth of the primary tumor that determines the prognosis for the patient, but whether it will spread and form metastases This process is very complex. There are often years between the development of the cancer and the aggressive growth of the metastases. Scientists from the German Cancer Research Center (DKFZ), the Stem Cell Institute HI-STEM*, the Ruhr University Bochum, Helmholtz Munich and ETH Zurich have studied and identified metastasis growth in breast cancer. They show: Not every breast cancer cell can lead to the development of metastases.


The German Cancer Research Center mourns the death of Harald zur Hausen. The Nobel Laureate in Medicine and longtime Chairman of the DKFZ Board of Directors died last Sunday, May 28, at the age of 87. "The news of Harald zur Hausen's death saddens all of us at DKFZ. Our thoughts are with his family. With him, we lose an outstanding scientist who made groundbreaking achievements in the field of tumor virology," said Michael Baumann, Chairman of the Board and Scientific Director of DKFZ. Epigenetic profiling identifies potential COPD treatment targets


Impaired function of lung fibroblast is considered causative for symptoms of the incurable lung disease COPD (Chronic Obstructive Pulmonary Disease). Using high-resolution epigenetic profiling, German and British scientists have now identified potential targets for COPD treatment. The team detected early epigenetic changes in the genome of COPD fibroblasts, providing new insights into the disease pathogenesis and potential therapeutic avenues.